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Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
2ykr S

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 12 D 37 R 1.22
2 30 P 50 A 1.00
3 23 V 47 L 0.91
4 22 A 47 L 0.79
5 20 E 43 N 0.78
6 11 I 41 F 0.70
7 16 L 20 E 0.66
8 34 W 57 H 0.66
9 69 H 74 F 0.62
10 72 G 77 T 0.61
11 21 K 25 S 0.60
12 88 K 92 K 0.59
13 58 V 75 A 0.58
14 49 I 62 V 0.55
15 33 T 71 L 0.53
16 39 T 70 K 0.53
17 10 F 14 H 0.50
18 69 H 73 E 0.48
19 84 A 92 K 0.47
20 87 K 92 K 0.47
21 16 L 41 F 0.47
22 7 K 11 I 0.46
23 22 A 27 D 0.45
24 20 E 24 E 0.45
25 17 K 21 K 0.45
26 19 V 49 I 0.44
27 53 N 75 A 0.44
28 14 H 18 K 0.44
29 87 K 91 K 0.42
30 2 P 37 R 0.41
31 50 A 59 P 0.41
32 56 Q 79 T 0.41
33 10 F 38 S 0.41
34 41 F 65 E 0.39
35 86 D 92 K 0.38
36 85 A 91 K 0.37
37 3 R 8 G 0.37
38 18 K 31 L 0.37
39 52 H 66 M 0.36
40 53 N 58 V 0.36
41 84 A 88 K 0.36
42 55 R 79 T 0.35
43 11 I 16 L 0.35
44 10 F 15 L 0.35
45 13 L 17 K 0.34
46 4 S 12 D 0.33

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness